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Example sentences for: ifkb

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Searches of the Dictyostelium sequence databases revealed two potential GCN2-like genes that we named ifkA and ifkB (initiation factor kinase).
The insert in IfkA and IfkB is significantly longer than that of other GCN2 proteins.
GCN2 of yeast and mammals is a known sensor of amino acid starvation and regulates cellular responses to such starvation [ 24 25 ] . Using degenerate primers and PCR and database searching identified two GCN2-like genes in Dictyostelium , ifkA and ifkB . Thinking that one or both of these genes may play a role in sensing amino acid starvation and in initiating development, we carried out the work described herein to examine their functions.
Several primers were designed to amplify and sequence the 5'-upstream sequences of the ifkA and ifkB ORFs.
In contrast, IfkB begins at the kinase domain and is the only known GCN2-like protein that does not possess a pseudokinase domain.