Words similar to ifkb
Example sentences for: ifkb
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The insert in IfkA and IfkB is significantly longer than that of other GCN2 proteins.
The predicted amino acid sequences of IfkA and IfkB are nearly identical within the kinase domain and the HisRS domain, and in turn these two domains share significant sequence identity with GCN2 proteins from yeast, Drosophila , and mammals.
2represents the additive mRNA levels from both genes in Ax4 during growth and development, while panel B reflects ifkB mRNA levels and panel C reflects ifkA mRNA levels.
GCN2 of yeast and mammals is a known sensor of amino acid starvation and regulates cellular responses to such starvation [ 24 25 ] . Using degenerate primers and PCR and database searching identified two GCN2-like genes in Dictyostelium , ifkA and ifkB . Thinking that one or both of these genes may play a role in sensing amino acid starvation and in initiating development, we carried out the work described herein to examine their functions.
The ifkA ORF contains 2258 amino acids, and the ifkB ORF contains 1360 (fig.