Words similar to hypersensitive
Example sentences for: hypersensitive
How can you use “hypersensitive” in a sentence? Here are some example sentences to help you improve your vocabulary:
Additional restriction mapping studies suggest that the hypersensitive regions are within the viral DNA fragment, and not in pUC DNA (data not shown).
DNase I hypersensitive cutting sites were seen at positions +32, +31, +30, +18, +4, -18, -19, -41, and -53 relative to the start of transcription.
One of these pathways stems from signals associated with hypersensitive cell death and is NPR1 -independent.
They also respond by the localized activation of a cell-death program, designated the hypersensitive response (HR), and by the systemic activation of cellular and molecular defenses, termed systemic acquired resistance (SAR) [ 1 2 3 4 5 6 7 ] . Second messengers that contribute to the development of the systemic response include reactive oxygen species (ROS), SA, JA and ethylene [ 8 9 10 ] . There is evidence for commonalities between plant responses to pathogens (referred to as defense responses) and environmental stresses (referred to as stress responses) [ 11 12 ] . Despite similarities, however, a plant's response to each environmental challenge is unique and tailored to increasing the plant's ability to survive the inciting stress [ 13 14 15 16 ] .
In response to DNA damage induced by ionizing radiation or chemical agents such as cisplatin, ATM kinase is activated and phosphorylates a number of downstream regulatory proteins important for cell cycle arrest, growth control, apoptosis and DNA repair [ 25 26 27 28 ] . AT patients are known to be predisposed to a variety of cancers, and the fibroblasts of AT patients are hypersensitive to ionizing radiation [ 29 ] . Although many reports showed the association of ATM mutation with risk of a number of different human malignancies, including prostate cancer, breast cancer, ovarian cancer, B-cell chronic lymphocytic leukemia and mantle cell lymphoma, the underlying molecular mechanism by which ATM gene causes these changes are not well understood [ 30 31 32 33 34 35 ] . There is so far no study showing the association of ATM gene with any solid tumor.
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