Words similar to hyperresponsiveness

Example sentences for: hyperresponsiveness

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It should be emphasized that NOD mice have a partial defect in thymic negative selection [ 25 26 ] , a defect in FcγRIIB (that can negatively regulate anaphylactic reactions [ 27 28 ] ), and perhaps other genetic polymorphisms that may result in immunological hyperresponsiveness.
In cell cultures of CD4 T cells and B cells from allergic individuals, addition of anti-CD81 antibody enhances IL-4 production from the T cells [ 19 ] . In mice, either complete lack of CD81, or lack of CD81 on B cells, leads to impaired humoral and Th2 immune responses [ 20 21 ] . Allergen-induced airway hyperresponsiveness is also decreased in CD81 nullmice [ 22 ] . Finally, lack of CD81 on murine T cells diminishes IL-4 production, with reduced expression of ICOS, GATA-3, STAT6 and phosphorylated STAT6 [ 23 ] .