Example sentences for: hypermethylation

How can you use “hypermethylation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The other four cell lines including the one with promoter hypermethylation (2102E-R) exhibited no detectable levels of RARB expression.

  • Loss of function of CDH1 gene has been shown to occur in widespread of epithelial tumor types by mutational or promoter hypermethylation mechanisms [ 11 20 ] . We have also identified loss of expression of CDH1 gene in 37.

  • To examine the biological role of promoter hypermethylation in GCT, we assessed the levels of gene expression by semi-quantitative RT-PCR in 23 tumors (15 NSGCTs and 8 SGCTs) with known methylation status.

  • The rare CpG hypermethylation seen in five SGCT patients may be due to the existence of a minor NSGCT component that might have escaped the histologic diagnosis.

  • Promoter hypermethylation was not found in normal testes for any of the tested genes except CDH1 . CDH1 exhibited methylation in two of the four normal testes analyzed.


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