Example sentences for: hypermethylation

How can you use “hypermethylation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Transcriptional silencing of genes resulting from DNA hypermethylation of CpG islands is reversed by treatment of the hypo-methylating agent 5-aza-2'-deoxycytidine in a dose and duration-dependent manner.

  • The rare CpG hypermethylation seen in five SGCT patients may be due to the existence of a minor NSGCT component that might have escaped the histologic diagnosis.

  • Gene expression is down regulated by promoter hypermethylation and reactivated by demethylation

  • However, hypermethylation was detected in one or more genes in 79 of 90 (87.

  • A most significant finding was that overall promoter hypermethylation is associated with the progression and predicts significantly poor disease-free survival.


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