Example sentences for: hypermethylation

How can you use “hypermethylation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • One cell line (T-218A) showed no promoter hypermethylation of MGMT by MSP and no detectable levels of mRNA expression by RT-PCR but expression was reactivated after 5-Aza-2' deoxycytidine treatment.

  • Four of the five SGCTs that exhibited promoter hypermethylation were methylated at a single locus and one tumor at two loci, whereas 27 of the 38 NSGCTs exhibited two or more methylated loci.

  • Promoter hypermethylation was not found in the DNA isolated from normal cervical smears for any of the tested genes.

  • Gene expression is down regulated by promoter hypermethylation and reactivated by demethylation

  • Here we show that hypermethylation is common in NSGCT and rare in SGCT.


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