Example sentences for: hyper-responsiveness

How can you use “hyper-responsiveness” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A hyper-responsiveness of AKXD28 ocular tissues to PAF or increased activity of the PTAFR receptor mediated signaling pathway could, therefore, contribute to the pronounced retinal damage through potentiating glutamate neurotoxicity.

  • The apparent GC hyper-responsiveness in LIFR null pups is probably not directly due to excess circulating corticosterone in the absence of LIFR.

  • A similar vascular hyper-responsiveness has been noted in caveolin-1 knock-out mice [ 25 26 ] raising the possibility that the accumulation of Gb 3 results in over-activity of uncoupled endothelial nitric oxide synthase within endothelial cell caveolae generating superoxide and other reactive oxygen species [ 27 ] . The latter may have a vasodilatatory effect [ 28 ] . Predominance of vascular abnormalities in the vertebro-basilar system in Fabry disease suggests fundamental biologic differences between the anterior and the posterior circulation.

  • The resulting pulmonary inflammation leads to bronchoconstriction, airway hyper-responsiveness, and ultimately to airway remodeling [ 1].


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