Words similar to hyper-recombination

Example sentences for: hyper-recombination

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Rec12 (Spo11) protein shares homology with the catalytic (Top6A) subunit of Topoisomerase VI, which functions as a heterotetramer with Top6B [ 16 17 ] . However, no Top6B homolog is present in most eukaryotes and the Rec12 (Spo11) enzyme does not need to affect strand passage in the manner of canonical type II topoisomerases [ 11 ] . We therefore tested whether overexpression of rec12 +would lead to a hyper-recombination phenotype, thereby implicating function as a homodimer.