Words similar to hpv-infected

Example sentences for: hpv-infected

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Converging evidence from epidemiological and molecular studies suggests that infection of genital human papillomavirus (HPV) is causally linked to the development of CC [ 4 ] . Since only a small fraction of HPV-infected cervical intra-epithelial neoplastic (CIN) lesions progress to invasive cancer, these studies further suggest that in addition to HPV, other host genetic factors play a role in cervical carcinogenesis [ 5 ] . A number of molecular studies have identified genetic alterations in these two histologic types of CC and at various stages of precursor lesions [ 6 7 8 ] . Despite this molecular characterization, the genetic basis of CC initiation and progression is still very poorly understood.
Converging points of evidence implicate infection by high-risk human papilloma virus (HPV) types as a critical etiologic factor in cervical tumorigenesis [ 1 ] . Epidemiological and experimental data, however, show that only a small fraction of HPV-infected cervical intraepithelial neoplastic (CIN) lesions progress to invasive cervical carcinoma (CC) [ 2 ] . These findings suggest somatic genetic mutations play a critical role in the initiation and progression of CC.