Words similar to holoenzyme

Example sentences for: holoenzyme

How can you use “holoenzyme” in a sentence? Here are some example sentences to help you improve your vocabulary:

However, the P protein is essential for the RdRP holoenzyme to exit the promoter and to form a closed complex that is capable of sustained elongation [ 20 ] . The preformed RdRP brought in by the infecting viral nucleocapsids catalyzes the first rounds of transcription, known as primary transcription.
In addition, BRCA1 can act as a transcriptional transactivator in yeast reporter assays [ 26, 27] and binds the RNA polymerase II holoenzyme, a component of the basal transcription machinery [ 25].
The recruitment model for transcriptional activation stipulates that eukaryotic transcription is driven mainly by recruitment of preformed RNA polymerase holoenzyme to specific sites on the DNA [ 3 ] . According to this model, peptides may bind one of numerous proteins that guide holoenzyme to the lexA binding site.
Given the diversity of proteins that comprise holoenzyme, this model implies that many sequences of different types would be competent activators; their sole requirement would be to bind proteins within holoenzyme [ 3 ] . The acidic peptides may interact in a manner akin to native activators [ 7 ] . But the basic ones may, for example, bind other proteins that contain acidic regions, thereby forming a bridge to holoenzyme.
Given that this domain lies in the periphery of the holoenzyme, it is likely to participate in interactions with cofactors, which is compatible with the protein-protein interaction function identified in several proteins with the β-grasp fold [ 80 81 ] .