Example sentences for: holoenzyme

How can you use “holoenzyme” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Given that this domain lies in the periphery of the holoenzyme, it is likely to participate in interactions with cofactors, which is compatible with the protein-protein interaction function identified in several proteins with the β-grasp fold [ 80 81 ] .

  • Such proteins include components of holoenzyme and perhaps other factors [see ref.

  • The recruitment model for transcriptional activation stipulates that eukaryotic transcription is driven mainly by recruitment of preformed RNA polymerase holoenzyme to specific sites on the DNA [ 3 ] . According to this model, peptides may bind one of numerous proteins that guide holoenzyme to the lexA binding site.

  • The subunit A protein is approximately 70 kDa in most organisms studied and is a hydrophilic peptide located in the head group of the V 1 peripheral sector in three copies per holoenzyme [ 18 ] . This subunit contains a nucleotide binding motif and functions to bind and hydrolyze ATP [ 19 ] . In addition, subunit A contains a highly conserved cysteine residue located within the enzymes' catalytic center that may be involved in regulation of the holoenzyme [ 20 21 22 23 ] . Cloning, sequencing and characteristics of subunit A of the V-Type ATPase from Arabidopsis thaliana have been previously reported [ 24 ] .

  • However, the P protein is essential for the RdRP holoenzyme to exit the promoter and to form a closed complex that is capable of sustained elongation [ 20 ] . The preformed RdRP brought in by the infecting viral nucleocapsids catalyzes the first rounds of transcription, known as primary transcription.


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