Words similar to holoapp

Example sentences for: holoapp

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Conversely, DN ROCK1 alone activated shedding of sAPP α . Cellular levels of holoAPP were not affected by transfection (Figure 5; p < 0.05 versus GFP control).
Typical maturation and half-life of mature cellular holoAPP were observed, as was subsequent release of sAPP α [5,29].
Treatment with atorvastatin increased csAPP by approximately 1.6-fold, similar to the effect of the drug on holoAPP (Figure 1), while sAPP α shedding was increased by approximately 7-fold ( p < 0.05).
In the presence of either atorvastatin or simvastatin, the time course of maturation and release perfectly paralleled that observed in the absence of either drug, except that the fractional content of cellular mature holoAPP was approximately 2-fold greater in the presence of drug (i.e.
Secretory maturation toxicity is one possible mechanism for elevated levels of intracellular mature holoAPP and causes retarded conversion of mature holoAPP to sAPP α . This pattern was not observed following statin treatment, excluding maturation toxicity as a mechanism underlying the altered levels of mature cellular holoAPP.