Words similar to hnoba

Example sentences for: hnoba

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This may suggest the possibility of the HNOBA domain binding some, as yet unknown, endogenous ligand.
Interestingly, binding studies on a synthetic pyrazolopyridine SGC agonist, BAY 41-2272 have suggested a role for the region 236-290 of the human SGC1 α-subunit in interacting with this ligand [ 25 26 ] . Though actual cross-linking occurred with cysteine residues situated just N-terminal to the HNOBA domain, it is likely that the rest of domain is involved in contact with the ligand.
Interestingly, the histidine kinases from the two cyanobacteria, and the GGDEF domain protein from Rhodobacter , which co-occur with solo HNOB domain proteins contain HNOBA domains at their extreme N-terminus (Fig.
Thus, even in the bacteria, the HNOBA domain always appears to function in association with the HNOB domain.
The co-occurrence of the HNOB and the HNOBA domains in either the same protein or proteins encoded by the same operon suggests a strong functional interaction between them.