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Example sentences for: hnoba

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Because the middle domain of the SGCs is always associated with the HNOB domains (see below), we named it the HNOBA ( HNOB A ssociated) domain.
The HNOB and HNOBA domains are likely to function synergistically or cooperatively.
Evolutionary history, domain architectures, and gene neighborhoods of the HNOB and HNOBA domain proteins
Interestingly, binding studies on a synthetic pyrazolopyridine SGC agonist, BAY 41-2272 have suggested a role for the region 236-290 of the human SGC1 α-subunit in interacting with this ligand [ 25 26 ] . Though actual cross-linking occurred with cysteine residues situated just N-terminal to the HNOBA domain, it is likely that the rest of domain is involved in contact with the ligand.
Given that these cyanobacterial HNOB proteins are also the closest bacterial relatives of the animal HNOB domains, it appears likely that the animal lineage acquired a related assemblage of HNOB and HNOBA domain as a single piece.