Words similar to hnoba

Example sentences for: hnoba

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The co-occurrence of the HNOB and the HNOBA domains in either the same protein or proteins encoded by the same operon suggests a strong functional interaction between them.
This suggests that the HNOBA domain could potentially contain a PAS-like fold.
All versions of the HNOBA domain, except one from Rhodobacter sphaeroides , contain a conserved histidine between the core region and the long C-terminal α-helix that links it to a kinase or cyclase domain (Fig.
Thus, even in the bacteria, the HNOBA domain always appears to function in association with the HNOB domain.
Interestingly, binding studies on a synthetic pyrazolopyridine SGC agonist, BAY 41-2272 have suggested a role for the region 236-290 of the human SGC1 α-subunit in interacting with this ligand [ 25 26 ] . Though actual cross-linking occurred with cysteine residues situated just N-terminal to the HNOBA domain, it is likely that the rest of domain is involved in contact with the ligand.