Example sentences for: hnoba

How can you use “hnoba” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Because the middle domain of the SGCs is always associated with the HNOB domains (see below), we named it the HNOBA ( HNOB A ssociated) domain.

  • This may suggest the possibility of the HNOBA domain binding some, as yet unknown, endogenous ligand.

  • Interestingly, binding studies on a synthetic pyrazolopyridine SGC agonist, BAY 41-2272 have suggested a role for the region 236-290 of the human SGC1 α-subunit in interacting with this ligand [ 25 26 ] . Though actual cross-linking occurred with cysteine residues situated just N-terminal to the HNOBA domain, it is likely that the rest of domain is involved in contact with the ligand.

  • The HNOB and HNOBA domains are likely to function synergistically or cooperatively.

  • The co-occurrence of the HNOB and the HNOBA domains in either the same protein or proteins encoded by the same operon suggests a strong functional interaction between them.


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