Example sentences for: hfe

How can you use “hfe” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • HFE mutation analysis and HLA typing of family members were performed to permit assignment of Ch6p haplotypes.

  • In each proband in whom a single A or B allele was detected by DNA-based typing, we verified the allele(s) and set phase to ascertain haplotypes of the proband using HFE and HLA analyses of appropriate family members.

  • The frequency of the A*03-B*07 haplotype was significantly increased in Alabama hemochromatosis probands without C282Y [ 23 ] , some of whom had the common HFE missense mutation H63D [ 23 ] . A*03-B*07 haplotypes associated with H63D have also been described in Alabama subjects with primary antibody deficiency [ 48 ] . Some Alabama subjects with hemochromatosis have an A*03-B*07 haplotype which includes the novel HFE missense mutation I105T [ 48 ] . Thus, a variety of HFE missense mutations occur in association with A*03-B*07 haplotypes in white Alabamians.

  • A variety of HFE missense mutations occur in association with A*03-B*07 haplotypes in white Alabamians.

  • For example, examination of the plots reveals that the hemochromatosis gene HFE, at 28 Mb on 6p, lies at the edge of a recombination 'cold spot' from 28-40 Mb.


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