Example sentences for: heme-binding

How can you use “heme-binding” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Studies on the human SGC1 suggest that the synthetic pyrazolopyridine ligand binds at site distinct from NO and heme, but requires the heme-binding site for its action [ 25 26 ] . This could imply a synergy or cooperation between these domains in heme interation and cyclase activation.

  • The multiple aligment shows that the heme-binding histidine of the SGC-β subunits is contained within this domain.

  • One of these, the HNOB domain, contains the heme-binding site of the SGCs and defines a family of small-molecule binding domains exclusively occurring in animals and bacteria.

  • The SGCs also contain a second globular domain situated in between the heme-binding and cyclase domains.

  • However, neither direct comparisons, nor sequence-structure threading revealed any relationship with the two other well-characterized α-helical heme-binding domains, namely globin and cytochrome C. Hence, it is likely that the HNOB domain adopts a structure distinct from these domains.


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