Words similar to heme
Example sentences for: heme
How can you use “heme” in a sentence? Here are some example sentences to help you improve your vocabulary:
However as a defense mechanism, availability of iron for the bacteria is limited in the host as most of it complexed to ferritin, transferrin, hemoglobin, heme and hemosiderin [ 1 2 3 4 ] . For pathogenic bacteria to be able to establish an infection, it must compete with and obtain iron from the host's iron binding protein [ 5 ] . The bacteria have evolved a number of diverse mechanisms utilize the host iron.
A variety of environmental small molecules, namely, nutrients, xenobiotics and first messengers are recognized by cells, with the help of specialized protein sensors on their surfaces [ 1 2 ] . Additionally cells also use protein-bound small molecules, such as FAD, cinnamic acid, tetrapyrroles and heme as sensors of photons and the ambient redox states [ 3 4 ] . Within cells, small molecules, such as cyclic nucleotides, are used as intracellular messengers to transduce signals arising from a variety of stimuli [ 1 2 ] . Over the past few years a combination of protein sequence analysis and biochemical studies have revealed several unifying principles that govern the recognition of small molecules by cells [ 4 5 6 7 8 9 ] . A significant component of small molecule-protein interactions is mediated via a relatively small set of ancient conserved protein domains that bind their ligands using specialized pockets [ 4 10 ] . Certain protein folds have given rise to several large superfamilies of ligand-binding domains.
Alternatively, IDO might influence COX activity and expression through competition for or release of heme, which both enzymes require.
The results of the RT PCR findings are summarized in Table 4. Of the antioxidant enzyme mRNAs measured, the only mRNA that differed significantly due to diet was the inducible form of heme oxygenase, which is identical to heat shock protein 32.
HO-1 catalyzes the breakdown of prooxidant heme to biliverdin with release of carbon monoxide and iron ion.
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