Words similar to hcdr
Example sentences for: hcdr
How can you use “hcdr” in a sentence? Here are some example sentences to help you improve your vocabulary:
Thus, in the setting of specific B-cell clonal expansion without concomitant cellular activation, the DNA-based fingerprinting assay will indicate a dominant HCDR3 length, whereas the cDNA-based assay may not (data not shown).
These individual HCDR3 lengths are signatures of the various individual B-cell clones contained within the polyclonal population.
This indicates that there are no dominant HCDR3 lengths that skew the Gaussian distribution, and therefore that there are no significant clonal expansions among the B cells that express most of these V H -C H combinations.
Note that when cDNA prepared from normal peripheral blood B cells is used as a template for these V H family-specific and C H -specific assays, ladders of HCDR3 lengths that differ by three nucleotides are identified.
It should be pointed out that when an individual HCDR3 length comprises more than 50% of the radioactive counts of a V H -C H ladder, clonality, based on DNA sequencing, is very likely; when an individual length comprises more than 70% of the radioactivity, clonality is virtually assured (data not shown).