Words similar to hcdr
Example sentences for: hcdr
How can you use “hcdr” in a sentence? Here are some example sentences to help you improve your vocabulary:
During normal B cell development, the processes of gene segment recombination and coding end processing yield nucleotide HCDR3 lengths that are characteristic and virtually invariant for an individual B-cell clone.
DNA sequence analyses of one of these two clones confirmed their identity, because each displayed the same rearranged V H DJ H gene with identical V H mutations and identical HCDR3 sequences (data not shown).
Conversely, in the setting of specific B-cell clonal activation without concomitant clonal expansion, the cDNA-based assay will indicate a dominant HCDR3 length, whereas the DNA-based assay may not.
Finally, in the setting of specific B-cell clonal activation with concomitant clonal expansion, both the cDNA- and the DNA-based assays will indicate a dominant HCDR3 length.
These individual HCDR3 lengths are signatures of the various individual B-cell clones contained within the polyclonal population.