Example sentences for: hcdr

How can you use “hcdr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Thus, in the setting of specific B-cell clonal expansion without concomitant cellular activation, the DNA-based fingerprinting assay will indicate a dominant HCDR3 length, whereas the cDNA-based assay may not (data not shown).

  • These individual HCDR3 lengths are signatures of the various individual B-cell clones contained within the polyclonal population.

  • This indicates that there are no dominant HCDR3 lengths that skew the Gaussian distribution, and therefore that there are no significant clonal expansions among the B cells that express most of these V H -C H combinations.

  • Note that when cDNA prepared from normal peripheral blood B cells is used as a template for these V H family-specific and C H -specific assays, ladders of HCDR3 lengths that differ by three nucleotides are identified.

  • It should be pointed out that when an individual HCDR3 length comprises more than 50% of the radioactive counts of a V H -C H ladder, clonality, based on DNA sequencing, is very likely; when an individual length comprises more than 70% of the radioactivity, clonality is virtually assured (data not shown).


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