Words similar to hb-egf

Example sentences for: hb-egf

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These negatively-charged EGF-like modules of LTBP-3 may interact efficiently with the positively-charged heparin-binding domain of both the membrane-bound and soluble forms of HB-EGF.
The trafficking of such growth factors as HB-EGF and TGF-β and structural proteins within the extracellular matrix is important in wound healing processes.
Recently it has been reported that treatment of EGF-responsive, nontransformed rat intestinal crypt cell line RIE-1 cells with TGF-β resulted in an increased level of expression of HB-EGF [ 16 ] . LTBP-3 is a protein that is ubiquitous in tissues and cells.
These are reasonable functions for the role of the proposed mHB-EGF :LTBP-3 protein:protein interactions as the expression of both mHB-EGF and TGF-β is important during extracellular matrix formation in wound healing [ 1 25 ] ; it has been suggested that the coordinated activities of HB-EGF and TGF-β regulate the wound healing process [ 16 ] .
The involvement of HB-EGF in various cellular and tissue functions and its presence in extracellular matrices suggested the possibility that it may interact with other extracellular matrix proteins.