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Example sentences for: hallmarks
How can you use “hallmarks” in a sentence? Here are some example sentences to help you improve your vocabulary:
Under defined in vitro conditions, these cells adopt a cardiomyocyte phenotype that goes beyond the simple expression of cardiac-restricted biochemical and molecular markers, extending to the types of single-cell physiological functions that are hallmarks of authentic cardiomyocytes, including action potentials, calcium transients, and contractile activity.
Thus, the present study identifies a new CD36-dependent molecular signaling pathway that mediates tubular epithelial apoptosis, and may underlie TED and IF, hallmarks of disease progression, specifically in human diabetic nephropathy.
And he contends that gotten is one of the hallmarks of American speech.
One of the hallmarks of cancer includes the accumulation of mutations in key genes, namely DNA repair genes [ 4 ] , tumor suppressor genes [ 5 6 ] , and proto-oncogenes [ 5 6 ] , accompanied by the loss of the wildtype allele, resulting in loss of heterozygosity [LOH, see reviews by [ 7 8 9 ] ]. Pancreatic cancer, which results in the death of approximately 30,000 Americans annually and is the fourth leading cause of cancer mortalities in the United States, exhibits this hallmark [ 10 ] . For example, in pancreatic cancer there is a high incidence of mutations (>50%) in the tumor suppressor genes p16, p53 and DPC4 and approximately 90% of cases coincide with a mutation in the oncogene K- ras 2 [see review by [ 11 ] ]. Furthermore, a significant percentage of tumors harboring a mutated copy of DPC4 or p53 also lose the corresponding wildtype allele, resulting in LOH [see reviews by [ 11 12 ] ].
The curvy contours, unexpected combinations of textures and materials, bright colors, and infinite detail are Gaudí hallmarks, as are his prevalent religious and nationalist symbolism.
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