Example sentences for: half-site

How can you use “half-site” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Genes with a conserved half-site for the Hap1p transcription factor, as well as a conserved Ecm22p/Upc2p binding site in their TCRs, were significantly associated with induction in the presence of drugs that inhibited ergosterol biosynthesis (Figure 5b).

  • The various Thr59 substitutions we constructed are all virtually as active as wild-type in heterodimer combinations with WT and with Y85H, the half-site A lesion (Table 3).

  • When different binding site lesions are introduced into the two subunits, thereby creating a mutant-mutant heterodimer, several outcomes are possible: If, for example, one lesion affects half-site A and the other affects half-site B, one of the RNA-binding sites is doubly defective, but the other is left intact.

  • However, the introduction of a mutation into one subunit of a single-chain heterodimer causes a defect in only one half-site and therefore inactivates only one of the two RNA-binding sites.

  • However, these new results show that a range of substitutions of Thr59 are well tolerated in half-site A, while a range of substitutions in half-site B compromise translational repression, each to a comparable extent.


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