Example sentences for: half-site

How can you use “half-site” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • When different binding site lesions are introduced into the two subunits, thereby creating a mutant-mutant heterodimer, several outcomes are possible: If, for example, one lesion affects half-site A and the other affects half-site B, one of the RNA-binding sites is doubly defective, but the other is left intact.

  • The deletion of the entire left half-site Fnr sequence, while preserving the right half-site as consensus, exhibited similar results (λJA304).

  • Heterodimers that contain either half site A lesions, or half-site B lesions in both subunits are inactive repressors.

  • We used Y85H to inactivate half-site A (where A-4 is bound) and T91I to inactivate half-site B (the site of A-10 interaction).

  • The various Thr59 substitutions we constructed are all virtually as active as wild-type in heterodimer combinations with WT and with Y85H, the half-site A lesion (Table 3).


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