Example sentences for: half-site

How can you use “half-site” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In the context of the work presented in this paper, this means that if a particular A-pocket mutation is functional for translational repression in combination with a lesion in half-site A, it must affect half site B where, from previous genetic and structural mapping, we know it interacts with A-10.

  • We think of each of the two equivalent, symmetry-related RNA-binding sites as being comprised each of two half-sites, where we define a half-site as representing the contribution of a subunit to one complete binding site (see Figure 3).

  • When different binding site lesions are introduced into the two subunits, thereby creating a mutant-mutant heterodimer, several outcomes are possible: If, for example, one lesion affects half-site A and the other affects half-site B, one of the RNA-binding sites is doubly defective, but the other is left intact.

  • The reader should also be alert to the possibility of confusing "A-pocket", which is shorthand for "adenosine-binding pocket", with the term "half-site A", which refers to those amino acids involved in binding RNA on subunit A of the coat protein dimer.

  • However, the introduction of a mutation into one subunit of a single-chain heterodimer causes a defect in only one half-site and therefore inactivates only one of the two RNA-binding sites.


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