Words similar to gshb

Example sentences for: gshb

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GshB: a different story
GshB appears to have arisen independently within bacteria and eukaryotes subsequent to the acquisition of the GshA gene.
We ran Shotgun with a query set containing six eukaryotic GshBs, eight bacterial GshBs, eight S6 modification enzymes (four from bacteria and four from archaea), and four proteins of unknown function (three from bacteria and one from the archaeon Methanococcus jannaschii ). Sample outputs are shown in Figure 7. Generally, sequences were found by either bacterial GshBs and the S6 modification enzymes, or by eukaryotic GshB proteins, but not by both groups.
The lack of conserved motifs in the substrate-binding region is consistent with the comparison of the E. coli and human GshB structures, which shows remarkably little similarity in this region of the protein.
After multiple iterations, a PSI-BLAST search using the E. coli GshB (gi121663) as an initial query sequence found 509 sequences of enzymes in the ATP-grasp superfamily, to which the bacterial enzyme is known to belong, but no eukaryotic GshB sequences.