Words similar to grs
Example sentences for: grs
How can you use “grs” in a sentence? Here are some example sentences to help you improve your vocabulary:
Thus, in the absence of physiological concentrations of PP5, GRs accumulate in the nucleus of A549 cells.
Alternatively, the data is also consistent with PP5 acting to promote the nuclear export of the GRs.
Like other steroid hormone receptors, GRs are phosphoproteins, and reversible phosphorylation of specific ser/thr residues on the GR or associated proteins has been implicated in the regulation of 1) hormone binding to the cytoplasmic GR-complex, 2) the translocation of the GR between the cytoplasm and the nucleus, 3) the binding of ligand activated GR to consensus GRE in the promoter regions of GR-responsive genes, and 4) the formation of an active transcriptional complex [ 1, 2, 5, 6, 7, 8, 28, 29, 30, 31].
Still, it is not yet clear if PP5 acts to suppress the nuclear accumulation or to facilitate the nuclear export of GRs.
These studies indicate that PP5 mediated suppression of GR-function arises from the ability of PP5 to suppress the nuclear accumulation of GRs.