Words similar to gr
Example sentences for: gr
How can you use “gr” in a sentence? Here are some example sentences to help you improve your vocabulary:
Glucocorticoids (CORT) function through the GR to both activate specific gene expression as well as transrepress NF-κB [ 41 ] . Since GR confers this latter effect by associating through protein-protein interactions with NF-κB bound at κB response elements [ 43 44 45 46 47 ] , it is important to also evaluate changes in GR protein levels (see below).
Since apparent defects due to LIFR loss arise during the late gestation GC surge, while maternal progesterone levels are declining in anticipation of birth and because phenotypes that have been attributed in the literature to GC excess are lessened through RU486 and the apparent heightened GC response in Lifr -/- mice affects both sexes equally, it is likely that RU486 attenuation of associated phenotypes is primarily mediated through GR antagonism.
This indicates that the improvement due to RU486 is implemented through modest alteration in GC regulation since complete loss of GR function leads to incomplete lung development at birth and impaired survival through atelectasis [ 77 ] . The neural compartment may have been under-protected by RU486 due to partial exclusion by the blood-brain-barrier, while bone and skeletal muscle, tissues exposed to higher levels of RU486, were clearly protected.
The declining PCNA and GR reflect the sharp decline in cell proliferation and branching; the increasing BMP1 and BMP3b similarly reflects inhibition of cell proliferation (Fig.
To further characterize the mechanism by which PP5 affects GR function, in the present study we employed a GR-GFP fusion protein and fluorescent microscopy to follow the movement of GR in cells treated with dexamethasone and ISIS 15534.