Words similar to gqα

Example sentences for: gqα

How can you use “gqα” in a sentence? Here are some example sentences to help you improve your vocabulary:

The determination of RGS specificity for receptor-G protein pairs are currently unknown; i.e., we and others have found that several RGSs interact with Gqα but only one, RGS3, has potent inhibitory activity on GnRH receptor signaling.
For instance, RGS4 and RGS-GAIP [ 11 ] , RGS3 [ 9 ] , RGS2 [ 46 ] , and RGS7 (our unpublished findings) all bind Gqα, the established G protein that transduces GnRH receptor signaling [ 38 ] . Nevertheless, RGS2 and 4 [ 9 ] , and RGS-GAIP and RGS7 (our unpublished data) are weak or null inhibitors of GnRH receptor signaling.
6), an effect that would be expected if the RGS3 inhibition was exerted at the level of the Gqα protein.
Because of the evidence that the signal transduction pathway for GnRH in gonadotropes involves the GnRH receptor, Gqα, phospholipase Cβ, and cellular IP 3 release [ 39 40 ] , we determined the effect of RGS3 on GnRH-stimulated LH secretion using adenoviral-mediated gene transfer in rat pituitary cells (Fig.
Moreover, our finding that GnRH-stimulated IP 3 production was inhibited supports the locus of the RGS3 effect as residing at phospholipase C or earlier in the transduction pathway, most likely at the Gα protein because of our studies both earlier [ 9 ] and here showing that RGS3 binds Gqα in vitro.