Example sentences for: gqα

How can you use “gqα” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These results confirm our previous findings that RGS3 interacts with Gqα but also show that it has significant interaction with all other Gα-proteins studied.

  • The determination of RGS specificity for receptor-G protein pairs are currently unknown; i.e., we and others have found that several RGSs interact with Gqα but only one, RGS3, has potent inhibitory activity on GnRH receptor signaling.

  • 6), an effect that would be expected if the RGS3 inhibition was exerted at the level of the Gqα protein.

  • Moreover, our finding that GnRH-stimulated IP 3 production was inhibited supports the locus of the RGS3 effect as residing at phospholipase C or earlier in the transduction pathway, most likely at the Gα protein because of our studies both earlier [ 9 ] and here showing that RGS3 binds Gqα in vitro.

  • RGS3 protein fused to glutathione-S-transferase (RSG3-GST fusion protein) was produced in the pGEX-5x-1 system of Pharmacia as detailed previously [ 9 ] . 35S-Met labeled Gα-proteins were prepared in vitro using a transcription/translation protocol [ 9 ] . cDNAs for Gqα [ 25 ] and Gzα [ 26 ] were obtained from M. I. Simon; for Gsα (ref.


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