Example sentences for: gqα

How can you use “gqα” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Because of the evidence that the signal transduction pathway for GnRH in gonadotropes involves the GnRH receptor, Gqα, phospholipase Cβ, and cellular IP 3 release [ 39 40 ] , we determined the effect of RGS3 on GnRH-stimulated LH secretion using adenoviral-mediated gene transfer in rat pituitary cells (Fig.

  • Significant (p < 0.05) amounts of Gi2α, Gi1α, Goα, and Gsα also were bound but were not as high as Gqα, Gzα, and Gi3α.

  • 6), an effect that would be expected if the RGS3 inhibition was exerted at the level of the Gqα protein.

  • A recent report seems to have clarified this issue: RGS4 must bind not only Gqα but also selected Gq-coupled receptors before it can inhibit receptor signaling [ 47 48 ] . Based on this finding, we propose that RGS3's binding to the GnRH receptor as well as to Gqα accounts for its specific inhibiting of GnRH receptor signaling.

  • More Gqα was bound by RGS3 than any other protein, although its binding was not significantly different from that of Gzα and Giα (p > 0.05).


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