Words similar to gqα

Example sentences for: gqα

How can you use “gqα” in a sentence? Here are some example sentences to help you improve your vocabulary:

Significant (p < 0.05) amounts of Gi2α, Gi1α, Goα, and Gsα also were bound but were not as high as Gqα, Gzα, and Gi3α.
RGS3 protein fused to glutathione-S-transferase (RSG3-GST fusion protein) was produced in the pGEX-5x-1 system of Pharmacia as detailed previously [ 9 ] . 35S-Met labeled Gα-proteins were prepared in vitro using a transcription/translation protocol [ 9 ] . cDNAs for Gqα [ 25 ] and Gzα [ 26 ] were obtained from M. I. Simon; for Gsα (ref.
6), an effect that would be expected if the RGS3 inhibition was exerted at the level of the Gqα protein.
Moreover, our finding that GnRH-stimulated IP 3 production was inhibited supports the locus of the RGS3 effect as residing at phospholipase C or earlier in the transduction pathway, most likely at the Gα protein because of our studies both earlier [ 9 ] and here showing that RGS3 binds Gqα in vitro.
A recent report seems to have clarified this issue: RGS4 must bind not only Gqα but also selected Gq-coupled receptors before it can inhibit receptor signaling [ 47 48 ] . Based on this finding, we propose that RGS3's binding to the GnRH receptor as well as to Gqα accounts for its specific inhibiting of GnRH receptor signaling.