Words similar to gqα
Example sentences for: gqα
How can you use “gqα” in a sentence? Here are some example sentences to help you improve your vocabulary:
Because of the evidence that the signal transduction pathway for GnRH in gonadotropes involves the GnRH receptor, Gqα, phospholipase Cβ, and cellular IP 3 release [ 39 40 ] , we determined the effect of RGS3 on GnRH-stimulated LH secretion using adenoviral-mediated gene transfer in rat pituitary cells (Fig.
Significant (p < 0.05) amounts of Gi2α, Gi1α, Goα, and Gsα also were bound but were not as high as Gqα, Gzα, and Gi3α.
6), an effect that would be expected if the RGS3 inhibition was exerted at the level of the Gqα protein.
A recent report seems to have clarified this issue: RGS4 must bind not only Gqα but also selected Gq-coupled receptors before it can inhibit receptor signaling [ 47 48 ] . Based on this finding, we propose that RGS3's binding to the GnRH receptor as well as to Gqα accounts for its specific inhibiting of GnRH receptor signaling.
More Gqα was bound by RGS3 than any other protein, although its binding was not significantly different from that of Gzα and Giα (p > 0.05).