Words similar to glycosylphosphatidylinositol
Example sentences for: glycosylphosphatidylinositol
How can you use “glycosylphosphatidylinositol” in a sentence? Here are some example sentences to help you improve your vocabulary:
The presence of CD59 on all annexin V-binding MP corresponds to the high expression of this glycosylphosphatidylinositol anchored glycoprotein on endothelial cells.
GPLD1 selectively hydrolyzes inositol phosphate linkages in vitro, releasing the protein bound to the plasma membrane via a glycosylphosphatidylinositol anchor into the cytosol [ 35 ] . P24 is a neuron specific membrane protein localized in intracellular organelles of highly differentiated neural cells and is involved in neural organelle transport.
Hyal-1 is a candidate tumor suppressor [ 5 18 ] , although it enhances extravasation and metastasis of prostate cancer cells [ 3 ] . Also, mutations in Hyal-1 may contribute to the pathogenesis of a lysosomal disorder, mucopolysaccharidosis IX [ 19 ] . Hyal-2 is a lysosomal protein, which is active at low pH [ 20 ] . This protein is also known to be a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for jaagsiekte sheep retrovirus [ 21 ] .
It is synthesized as a 69 kDa precursor that is proteolytically processed into a 40 kDa membrane bound form that is glycosylphosphatidylinositol (GPI)-linked and a 32 kDa secreted form.
Hyal-2 is found in the lysosome and is active under conditions of low pH [ 20 ] . Hyal-2 is also found on the cell surface as a glycosylphosphatidylinositol (GPI)-anchored receptor for jaagsiekte sheep retrovirus [ 21 ] . Nonetheless, the enzymatic activity of Hyal-2 has not been detected [ 21 ] . Whether the increased TNF cytotoxicity in L929 cells caused by Hyal-1 and Hyal-2 is associated with their enzymatic activities is being studied in this laboratory.
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