Words similar to glycine-conjugated
Example sentences for: glycine-conjugated
How can you use “glycine-conjugated” in a sentence? Here are some example sentences to help you improve your vocabulary:
This leaves the possibility that conjugated bile acids may activate the apoptotic cascade through Fas receptor in this cell line, as glycine-conjugated bile acids do in hepatocytes [ 25 ] . However, the activation of caspases does not require a specific kind of bile acid transporter since TCA is not toxic to McArdle RH-7777 cells irrespective of whether these cells internalize bile acids via ntcp or asbt.
Liver cells, which normally metabolize bile acids, apparently possess a mechanism that can distinguish and differentially elaborate distinct biological activities of taurine- and glycine-conjugated bile acids.
The latter finding indicates that taurine-conjugated bile acids are capable of inducing apoptosis when PI3K is inhibited, probably by utilizing the same mechanism activated by glycine-conjugated bile acids.
However, the different profile of caspase 8 activation suggests that taurine- and glycine-conjugated bile acids may trigger apoptosis by different pathways.
Therefore, the presence of an intracellular bile acid binding protein did not protect these cells from glycine-conjugated bile acid cytotoxicity, even at low bile acid concentrations.
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