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Example sentences for: giardia
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However, the absence of such a basic cluster in the N-terminal domains of Giardia (residues 1-25) and Schizosaccharomyces pombe (data not shown) renders its significance questionable.
Separately, for timing the origin of Giardia , sequences of 17 proteins were obtained from the public databases and aligned [ 37 ] in which the following taxa were available: Giardia and other eukaryotes (including calibration taxa; see below), archaebacteria, and eubacteria.
Although the position of Giardia in some protein phylogenies [ 30 ] has been proposed as evidence that it is a secondary amitochondriate, others have urged caution until additional, more conclusive, data become available [ 6 ] .
The overall alignment of the midasin M-domain from humans, yeast and Giardia with other MIDAS-containing proteins (three Mg-chelatases and the I-domains of three integrins) was created by first aligning the midasins, Mg-chelatases and integrins separately with the program T-Coffee [ 58 ] . The resultant three partial alignments were then combined by the profile alignment procedure of ClustalX, as above.
However, the major truncation of the midasin N-terminal domain in Giardia (Fig.