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Example sentences for: giardia
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Separately, for timing the origin of Giardia , sequences of 17 proteins were obtained from the public databases and aligned [ 37 ] in which the following taxa were available: Giardia and other eukaryotes (including calibration taxa; see below), archaebacteria, and eubacteria.
The midasin gene in Giardia intestinalis (accession AF494287) was cloned in silico from sets 1-11 of the unassembled genomic nucleotide sequences kindly made available by the Giardia Genome Project [ 11 ] . Regions of conserved amino acid sequence in the human and yeast genes for midasin were used as input to the Tblastn server at Genbank [ 56 ] to identify clones that encoded homologous regions in Giardia.
However, in the compacted genome of Giardia [ 11 12 ] ., the N-terminal domain is greatly truncated and consists of only about 25 residues.
The importance of Giardia is its lack of mitochondria and basal location in many phylogenies of eukaryotes [ 27 39 ] .
The ortholog in these species, as well as the presence of an unassembled orthologous gene in humans, Caenorhabditis and Giardia, has been noted by Mocz and Gibbons [ 6 ] , who discussed its evolutionary relationship to the heavy chain of dynein motor protein.