Words similar to giantin

Example sentences for: giantin

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The identified autoantigens referred to are golgin-160/GCP170 [ 7 8 ] , golgin-95/gm130 [ 7 ] , golgin-97 [ 9 ] , golgin-245/ p230 [ 10 11 12 ] , giantin/macrogolgin/GCP372 [ 13 14 ] , and golgin-67 [ 15 ] . These proteins are characterized by predominant α-helical coiled-coil domains, except for N-termini and C-termini.
These proteins include yeast Osh3p, a cytoplasmic oxysterol-binding protein, animal Sec14-like proteins that are involved in secretion, human GCP60 (also called PAP7, a peripheral-type benzodiazepine receptor-associated protein [ 14]), which interacts with the Golgi integral membrane protein Giantin, and several other uncharacterized eukaryotic proteins with different lipid-binding domains (Figure 1).
A region of the GPC60 molecule that rather precisely encompasses the GOLD domain has been shown to bind to the cytoplasmic region of the Golgi membrane protein Giantin [ 16].
The processing of golgin-160 and giantin occurred as early as that for PARP, suggesting that these proteins are cleaved during the onset of apoptosis (data not shown).
Similar staining patterns to those seen with golgin-97 were observed when apoptotic HEp-2 cells were stained with antibodies to golgin-95, golgin-160, golgin-245, and giantin (data not shown).