Example sentences for: genotype-phenotype

How can you use “genotype-phenotype” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It has been reported that 40% of mutations identified in the region between exons 59-65, but only 7% of mutations in other regions, were associated with mild Marfan-like phenotypes [ 12 ] . Our results are in line with the notion of this general genotype-phenotype correlation.

  • For the case of RNA secondary structure folding, this property of the genotype-phenotype map has been demonstrated analytically using graph theory [ 41 ] , and it has been verified in extensive numerical simulations [ 42 43 ] . Random graph theory predicts that RNA secondary structures can be classified into common structures, which can be found almost anywhere in sequence space, and rare structures.

  • These case studies were chosen to further investigate the metabolic genotype-phenotype relation in silico and to demonstrate the use of FBA to interpret and analyze cellular metabolism.

  • Whereas most published genotype-phenotype correlation studies compare the nucleotide changes at the DNA level with the list of phenotypic features, we feel strongly that studies of the mutant alleles at the RNA and protein level are necessary to take some of the guesswork out of these correlations.

  • Note that this is not a model for the evolution of genotype frequencies or for the maintenance of MHC heterozygosity, but simply an algebraic framework for predicting the outcome of an epidemiological study of the type cited above, given current allele frequencies and genotype-phenotype mappings.


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