Words similar to genital
Example sentences for: genital
How can you use “genital” in a sentence? Here are some example sentences to help you improve your vocabulary:
To gain insights into the role of androgen in genital morphogenesis, we compared basal transcriptional patterns in genital fibroblasts from 46,XY individuals with either wild-type AR or germline inactivation of the AR as a result of mutation.
Converging evidence from epidemiological and molecular studies suggests that infection of genital human papillomavirus (HPV) is causally linked to the development of CC [ 4 ] . Since only a small fraction of HPV-infected cervical intra-epithelial neoplastic (CIN) lesions progress to invasive cancer, these studies further suggest that in addition to HPV, other host genetic factors play a role in cervical carcinogenesis [ 5 ] . A number of molecular studies have identified genetic alterations in these two histologic types of CC and at various stages of precursor lesions [ 6 7 8 ] . Despite this molecular characterization, the genetic basis of CC initiation and progression is still very poorly understood.
Compared to LNCaP cells, normal male genital fibroblasts show distinctly lower baseline expression of several AR co-regulators (such as NCOA2 (GRIP-1), NCOA3 (TRAM-1), ARA54 (RNF14), data not shown).
In vivo protection by anti-HIV-1 compounds against sexual transmission of the virus could only be accomplished if the compounds at sufficient concentrations, and the virus both reach susceptible cells within genital mucosa before productive infection could occur [ 38 39 ] . Considering the complex events involved in sexual transmission of HIV-1, this might not be easily accomplished.
Therefore, the AR appears to be involved in setting long-lasting gene-expression patterns in genital skin fibroblasts.
Loading...