Example sentences for: gatekeeper

How can you use “gatekeeper” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The rapid time course of induction and sensitivity of CaT1 mRNA response to 1,25-dihydroxyvitamin D treatment supports the idea that CaT1 could play a role as a gatekeeper of intestinal calcium absorption.

  • This regulatory genomic response of the enterocyte would result in an increase in the brush border membrane content of CaT1 calcium influx channels that could function as a gatekeeper mechanism to augment the rate of calcium entry across the apical membrane [ 9 ] . However, given that there is a Ca-dependent negative feedback mechanism to limit calcium entry through the channel by maintaining the channel in the closed position [ 14 15 ] there must be a way to remove calcium from the vicinity of the cytosolic face of the channel to optimize and sustain calcium influx rates.

  • Enter the AFI--a gatekeeper that, true to its times, has yielded to more commercial concerns.

  • The Office of Intelligence Policy and Review became the gatekeeper for the flow of FISA information to criminal prosecutors.

  • Thus, in the current study, to evaluate a possible gatekeeper role for CaT1 in vitamin D-mediated calcium transport we compared the time course of 1,25-dihydroxyvitamin D induction of calbindin D9k mRNA and CaT1 mRNA in Caco-2 cells.


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