Words similar to gatekeeper
Example sentences for: gatekeeper
How can you use “gatekeeper” in a sentence? Here are some example sentences to help you improve your vocabulary:
Thus, in the current study, to evaluate a possible gatekeeper role for CaT1 in vitamin D-mediated calcium transport we compared the time course of 1,25-dihydroxyvitamin D induction of calbindin D9k mRNA and CaT1 mRNA in Caco-2 cells.
Most of it is uncritical, otherwise journalistic access to the big names in the casts and the films with big numbers in their budgets is denied by the gatekeeper publicists."
This regulatory genomic response of the enterocyte would result in an increase in the brush border membrane content of CaT1 calcium influx channels that could function as a gatekeeper mechanism to augment the rate of calcium entry across the apical membrane [ 9 ] . However, given that there is a Ca-dependent negative feedback mechanism to limit calcium entry through the channel by maintaining the channel in the closed position [ 14 15 ] there must be a way to remove calcium from the vicinity of the cytosolic face of the channel to optimize and sustain calcium influx rates.
the beatific-looking gatekeeper asks with amusement.
In any case, the demonstrated effect of 1,25-dihydroxyvitamin D on CaT1 mRNA shown here in Caco-2 cells is consistent with the idea that the active metabolite of vitamin D could increase the number of CaT1 calcium transporters in the plasma membrane and could therefore be responsible for the higher rates of calcium influx seen across the brush border membrane in vitamin D-replete animals [ 9 27 ] thereby playing a key gatekeeper role in increasing the efficiency of intestinal calcium absorption and maintaining calcium homeostasis.
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