Words similar to gastritis
Example sentences for: gastritis
How can you use “gastritis” in a sentence? Here are some example sentences to help you improve your vocabulary:
Given that gastritis, whether it is induced by infection with H. pylori or toxicity responses to NSAIDs, is associated with NF-κB activation, TNFα expression and apoptosis in epithelial cells [ 5 6 7 ] , strategies to limit these responses may have significant therapeutic potential.
The resultant nitrotyrosine is used as a marker of peroxynitrite or at least nitration reactions in gastritis [ 13 ] , inflammatory bowel disease [ 15 16 ] as well as general inflammation [ 17 ] . While we have demonstrated that peroxynitrite-induced apoptosis of macrophages and colon epithelial cells is reduced by ascorbic acid [ 18 ] , it is not known if other dietary antioxidants exert similar benefits or if they are present in epithelial cells from the upper gastrointestinal tract.
The early indicator for the subject predisposed to GC is abnormal hyperproliferation of gastric epithelial cells, such as chronic atrophic gastritis (CAG), DYS and intestinal metaplasia (IM), which have been considered as precancerous lesions of GC (You et al.
Indeed that is a concern that has been raised following the failure of prospective antioxidant trials in smokers to limit the incidence/progression of lung cancer [ 35 ] and the recent epidemiological analysis of gastric cancer incidence and green tea consumption [ 32 ] . However, other evidence has indicated that the antioxidants, vitamin E or N-acetylcysteine, enhanced the ability of the chemotherapeutic agent 5-fluorouracil to induce apoptosis in colon cancer cells [ 36 ] . These in vitro observations are supported by the Apc minanimal model [ 32 ] and sustained clinical trial in patients with H. pylori gastritis [ 30 ] suggesting that dietary antioxidants do not exacerbate precancerous states but may indeed promote regression.
Recently, both green tea and cat's claw have been reported to reduce the expression of inflammatory genes; responses that are linked to apoptosis and proliferation [ 23 24 25 26 27 ] . Indeed, cat's claw has been described as a potent inhibitor of the transcription factor NF-κB activation, preventing the expression of TNFα and inducible nitric oxide synthase [ 23 24 ] . These immune/inflammatory products are associated with gastritis and epithelial cell death [ 5 6 7 13 ] and hence cat's claw may have utility in limiting gut inflammation [ 23 ] . Indeed, this matches its ethnomedical use in South America where it is used to treat gastritis and other forms of chronic inflammation like arthritis [ 28 ] . Green tea, and its constituent polyphenols, has been associated with reduced expression of inflammatory genes and signal transduction processes leading to cell death [ 21 25 26 27 ] .
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