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Example sentences for: fusion-linked
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The pair of fusion-linked COGs 0777 and 0825 (α and β subunits of acetyl-CoA carboxylase, respectively) shows unequivocal clustering of the fusion components from numerous archaeal and bacterial species, which indicates a prevalent role for HGT in the evolution of this fusion (Figure 5a,5b).
A search of the COGs database revealed 405 pairs of fusion-linked COGs.
Only 52 pairs of fusion-linked COGs included fusions represented in two or three kingdoms (Table 1), and for reasons discussed above, we chose these pairs of COGs for an evolutionary analysis of gene fusions.
By investigating the phylogenies of each of the two fusion-linked genes, it may be possible to determine the evolutionary scenario for the fusion itself.
To distinguish between a single fusion event followed by HGT and/or fission of the fused gene and multiple, independent fusion events in distinct organisms, we analyzed phylogenetic trees that were constructed separately for each of the fusion-linked domains (proteins).
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