Words similar to fusion-linked
Example sentences for: fusion-linked
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A search of the COGs database revealed 405 pairs of fusion-linked COGs.
To distinguish between a single fusion event followed by HGT and/or fission of the fused gene and multiple, independent fusion events in distinct organisms, we analyzed phylogenetic trees that were constructed separately for each of the fusion-linked domains (proteins).
The fusion-linked COGs 1605 and 0077 (chorismate mutase and prephenate dehydratase, respectively) show a more complicated history, with distinct fusion events resulting in different domain architectures (see legend to Figure 4).
Thus, the history of this pair of fusion-linked COGs appears to involve horizontal transfer of the fused gene between bacteria and archaea (and possibly also within kingdoms), as well as at least one additional, independent fusion event in bacteria.
In contrast, only 14 fusion-linked pairs of COGs show evidence of independent fusion in two kingdoms, and in just two cases, the fusion seems to have been inherited from the last universal common ancestor.
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