Words similar to fusion-linked
Example sentences for: fusion-linked
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In contrast, only 14 fusion-linked pairs of COGs show evidence of independent fusion in two kingdoms, and in just two cases, the fusion seems to have been inherited from the last universal common ancestor.
Only 52 pairs of fusion-linked COGs included fusions represented in two or three kingdoms (Table 1), and for reasons discussed above, we chose these pairs of COGs for an evolutionary analysis of gene fusions.
A gene fusion is presumably fixed during evolution only when the partners cooperate functionally and, by inference, a functional link can be predicted to exist between fusion-linked genes.
The fusion-linked COGs 1605 and 0077 (chorismate mutase and prephenate dehydratase, respectively) show a more complicated history, with distinct fusion events resulting in different domain architectures (see legend to Figure 4).
To distinguish between a single fusion event followed by HGT and/or fission of the fused gene and multiple, independent fusion events in distinct organisms, we analyzed phylogenetic trees that were constructed separately for each of the fusion-linked domains (proteins).