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Example sentences for: fusion-linked
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The pair of fusion-linked COGs 0777 and 0825 (α and β subunits of acetyl-CoA carboxylase, respectively) shows unequivocal clustering of the fusion components from numerous archaeal and bacterial species, which indicates a prevalent role for HGT in the evolution of this fusion (Figure 5a,5b).
Figure 2shows the pair of phylogenetic trees for the fusion-linked COGs 1788 and 2057.
The fusion-linked COGs 1605 and 0077 (chorismate mutase and prephenate dehydratase, respectively) show a more complicated history, with distinct fusion events resulting in different domain architectures (see legend to Figure 4).
Only 52 pairs of fusion-linked COGs included fusions represented in two or three kingdoms (Table 1), and for reasons discussed above, we chose these pairs of COGs for an evolutionary analysis of gene fusions.
In contrast, only 14 fusion-linked pairs of COGs show evidence of independent fusion in two kingdoms, and in just two cases, the fusion seems to have been inherited from the last universal common ancestor.
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