Words similar to fsgs
Example sentences for: fsgs
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The diagnosis of FSGS was made on Periodic acid–Schiff staining in the absence of immunodeposits on electron microscopy.
In addition, we did not observe increased proximal tubular CD36 expression in kidney biopsy samples from patients with FSGS (Figure 1J), that were matched with DNP samples for the severity of proteinuria (all in the nephrotic range) and renal insufficiency (all with elevated serum creatinine; 1.7–5.
Semi-quantitative analysis of the distribution and intensity of CD36-positive PTECs (CD36 PTEC score), which was performed by two independent pathologists in a blinded manner, demonstrated that mean CD36 PTEC scores were not different between FSGS kidneys and normal human kidneys, but were significantly increased in DNP kidneys (Figure 1K).
In addition, tubular epithelial apoptosis was increased, but highly variable, in FSGS kidneys (data not shown).
Importantly, biopsy samples from cases of FSGS that were matched for degree of proteinuria, renal function, and hypertension were characterized by TED, IF, and increased tubular epithelial apoptosis; however, proximal tubular CD36 expression was similar to that in normal human control kidney.