Words similar to frizzled
Example sentences for: frizzled
How can you use “frizzled” in a sentence? Here are some example sentences to help you improve your vocabulary:
Perhaps down-regulation of frizzled family members by IL-1β is deleterious to chondrocyte function and can contribute to OA.
Of potential importance is the fact that frizzled family members have recently been implicated by Carson and colleagues in rheumatoid arthritis [ 53].
Moreover, Frizzled receptors, Versican and other proteoglycans which contribute to Wnt protein activity are also controlled by Wnt signaling, as previously described in Drosophila [ 28 29 ] . At the level of transcriptional regulation, we found up-regulation of CBP/P300, which partners with β-catenin [ 30 31 ] but also TLE/Groucho, which is an inhibitor of TCF function [ 32 ] . These responses suggest a rich system of homeostasis and feedback control mechanisms, but they complicate the interpretation of experimental studies of Wnt signal transduction in which the time course of induction cannot be controlled easily.
, without co-expressing LRP5/6) preferentially activate the Wnt/beta-catenin or Wnt/Ca 2+pathways [ 5 ] . Interestingly, Wnt-5a may couple to either pathway depending on which frizzled receptor is present.
This effect requires the aminoterminus of DFz2, implying a requirement for binding Wg to the Fz CRD, but not the carboxyterminus, suggesting that the signal may be, in part, transmitted through an interaction of Wg-Frizzled complex with another protein.
Loading...