Words similar to frizzled

Example sentences for: frizzled

How can you use “frizzled” in a sentence? Here are some example sentences to help you improve your vocabulary:

When co-expressed with human frizzled-5, Wnt-5a can induce a secondary axis in Xenopus [ 10 ] . In other assays, however, Wnt-5a along with rat frizzled 2 (Rfz-2) increases intracellular Ca 2+levels and activates PKC and CamKII [ 4 5 6 ] . The activation of Wnt/Ca 2+signaling by Wnt-5a and Rfz-2 seems to be antagonistic to the canonical Wnt signaling pathway.
In addition, an antibody to Wnt-3A itself was used for depletion, although it worked less efficiently than the Frizzled fusion protein
Mis-regulation of Wnt signaling leads to the development of several human cancers, including colon carcinomas and melanoma [ 1 ] . Canonical Wnt signaling initiates in the binding of a Wnt ligand to its cell surface receptor, members of the frizzled gene family, along with the co-receptor LRP5/6 [ 2 3 ] , leading to changes in the activities of cytoplasmic effectors resulting in the stabilization of beta-catenin protein.
, without co-expressing LRP5/6) preferentially activate the Wnt/beta-catenin or Wnt/Ca 2+pathways [ 5 ] . Interestingly, Wnt-5a may couple to either pathway depending on which frizzled receptor is present.
Despite the cancerous origin of these cells, they share many properties with embryonic stem cells [ 7 ] . These cells express several members of the Frizzled family (including FZD7), one of the receptors for Wnt (data not shown; Figure 2A).