Words similar to frizzled

Example sentences for: frizzled

How can you use “frizzled” in a sentence? Here are some example sentences to help you improve your vocabulary:

Mis-regulation of Wnt signaling leads to the development of several human cancers, including colon carcinomas and melanoma [ 1 ] . Canonical Wnt signaling initiates in the binding of a Wnt ligand to its cell surface receptor, members of the frizzled gene family, along with the co-receptor LRP5/6 [ 2 3 ] , leading to changes in the activities of cytoplasmic effectors resulting in the stabilization of beta-catenin protein.
, without co-expressing LRP5/6) preferentially activate the Wnt/beta-catenin or Wnt/Ca 2+pathways [ 5 ] . Interestingly, Wnt-5a may couple to either pathway depending on which frizzled receptor is present.
The basis for the development of this planar or tissue polarity has principally been studied in Drosophila [ 1 2 3 4 ] where it is under the control of the frizzled ( fz ) pathway [ 5 ] . Many Drosophila epidermal cells produce cuticular hairs that are outgrowths from the apical surface of pupal epidermal cells.
A new frizzled family member that is expressed in chondrocytes and is involved in skeletal morphogenesis has been described [ 54].
When co-expressed with human frizzled-5, Wnt-5a can induce a secondary axis in Xenopus [ 10 ] . In other assays, however, Wnt-5a along with rat frizzled 2 (Rfz-2) increases intracellular Ca 2+levels and activates PKC and CamKII [ 4 5 6 ] . The activation of Wnt/Ca 2+signaling by Wnt-5a and Rfz-2 seems to be antagonistic to the canonical Wnt signaling pathway.