Example sentences for: fpm

How can you use “fpm” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Clearly, at this time, the rate of drug metabolism for an oral input must be identical to that for an IV input so that FPM must be zero, even though a large fraction of the absorbed drug may be metabolized in its first pass through the liver.

  • The FPM for this data was also estimated by using the one compartment approach [ 3 ] . Figure 5Ashows the optimized one compartment Michaelis-Menten fit to the tail of the venous ethanol data (Vm = 8.68 millimoles/min; Km = 5.46 mM).

  • The error in both these approximations to FPM results primarily from the fact that the systemic appearance of the oral ethanol taken with a meal is slow compared to the 20 minute constant infusion that was used to obtain the IV AUC.

  • This is the first human PBPK model for ethanol incorporating intestinal absorption and FPM.

  • The definition of FPM implemented in PKQuest is both rigorous and intuitive.


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