Words similar to fpm

Example sentences for: fpm

How can you use “fpm” in a sentence? Here are some example sentences to help you improve your vocabulary:

For the non-linear case, the intuitive idea that FPM is equal to the fraction of the absorbed drug that is metabolized in its first pass through the liver is no longer valid [ 2 ] . Consider the case where GI absorption is occurring at a time when the systemic drug concentration is so high that the liver metabolism is completely saturated and the metabolic rate is constant, independent of concentration.
This would correspond to a FPM of 73% if metabolism was linear - i.e. only 27% of the orally ingested ethanol reaches the systemic circulation.
This is much less than the FPM value of 44% determined by using the AUC approach or of 30% using the one compartment approach.
. As will be shown below, the actual FPM is much less than this.
The fractional FPM is then defined as the fractional difference in these two areas: