Words similar to follistatin
Example sentences for: follistatin
How can you use “follistatin” in a sentence? Here are some example sentences to help you improve your vocabulary:
The chimeric protein containing BMPR-IA was chosen because it has been previously reported that this is the predominant BMP receptor type expressed in embryonic and postnatal superior cervical ganglia (SCG) [ 29 ] . As indicated in Figure 5, follistatin and noggin significantly inhibit the dendrite promoting activity of BMP-5 in a concentration-dependent manner.
Mutating the single TCF binding site on the Follistatin promoter eliminated the response.
Moreover, we found that a luciferase reporter gene, placed under the control of the Follistatin promoter, was activated by Wnt-3A protein added to transiently transfected NCCIT cells (Figure 5).
The bone morphogenetic protein (BMP) family including ligands, receptors, and binding proteins, has emerged as a central player in ovary physiology and female fertility [ 1 ] . The BMPs represent a large subclass of the transforming growth factor-β (TGF-β) surperfamily of ligands whose biological responses are mediated by Ser/Thr kinase receptors via the Smad-signaling molecules [ 2 ] . The mRNAs encoding several BMP family members have been identified in the murine ovary, including the ligands, BMP-2 [ 3 ] , BMP-3 [ 3 ] , BMP-3b [ 3 ] , BMP-4 [ 4 ] , BMP-6 [ 5 ] , BMP-7 [ 4 ] , BMP-15 [ 6 7 8 ] , the BMP receptors, BMPR-IA, BMPR-IB and BMPR-II [ 4 ] and the BMP binding protein, follistatin (FS) [ 9 ] . In the murine, BMP-4 and -7 mRNA have been identified in the theca interstitial cells [ 4 ] , BMP-6 and -15 in oocytes [ 5 6 7 8 ] , BMPR-IA, BMPR-IB and BMPR-II in oocytes and granulosa cells (GCs) [ 4 ] , and FS in granulosa and lutein cells [ 9 10 ] .
These data suggest that Follistatin is activated directly through the Wnt signal transduction pathway and not by another pathway.
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