Words similar to folliculogenesis

Example sentences for: folliculogenesis

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Equally important, other studies have shown that loss-of-function and naturally occurring mutations in BMP ligands and receptors are associated with dysregulation of folliculogenesis and ovulation [ 14 15 16 17 18 19 ] . Of particular interest is the finding that ewes having a mutation in the bmp15 gene in both alleles are infertile whereas the heterozygotes are superfertile [ 16 ] . Thus, the bmp15 gene can control ovulation quota through a dosage-sensitive mechanism.
During folliculogenesis, the theca cells (T) of the theca interna (TI) and externa (TE) of dominant follicles strongly expressed BMP-3b mRNA (Fig.
In vitro experiments with rat GCs have demonstrated that BMP-4 and -7 inhibit and stimulate FSH-induced progesterone and estradiol production, respectively [ 4 ] . In related studies BMP-6 and BMP-15 were found to block FSH action through inhibiting FSH-dependent adenylate cyclase activity and FSH receptor expression, respectively [ 11 12 ] . The importance of these findings is underscored by the fact that FSH action is obligatory for normal folliculogenesis and female fertility.
In the theca, the levels of BMP-4 mRNA change during folliculogenesis.
This, together with the failure to detect BMP-4 and 7 in the theca of atretic follicles, supports the idea that the cellular sites and coordinate expression of these BMP genes may have important regulatory roles in maintaining folliculogenesis.