Words similar to fluoxetine
Example sentences for: fluoxetine
How can you use “fluoxetine” in a sentence? Here are some example sentences to help you improve your vocabulary:
For example, chronic treatment with fluoxetine decreases the release of AVP from rat hypothalamic organ cultures [ 36 ] . This finding is particularly noteworthy since alterations in AVP levels in the cerebrospinal fluid have been correlated with occurrences of OCD [ 15 16 ] . The occurrence of OCD has also been correlated with increased levels of oxytocin, a neuropeptide closely related to AVP [ 37 ] . In golden hamsters, the elevation of serotonin in the anterior hypothalamus following fluoxetine treatment can inhibit the activity of the AVP system related to aggressive behavior [ 10 11 ] . The ability of microinjected AVP in the anterior hypothalamus to enhance aggressive behavior in golden hamsters is blocked by fluoxetine treatment and serotonin 5HT 1A receptor agonists [ 10 ] . The present data include AVP-stimulated flank marking in the list of behaviors suppressed by fluoxetine treatment.
Clomipramine is a non-selective re-uptake inhibitor of serotonin, and to some extent norepinephrine [ 21 ] and fluoxetine is a selective serotonin re-uptake inhibitor [ 22 ] . Both of these drugs have proven to be effective in different animals models of OCD [ 23 ] . As an additional control, hamsters were also treated with desipramine, a noradrenergic re-uptake inhibitor [ 24 ] that has been found ineffective in inhibiting OCD in preclinical [ 25 ] and clinical studies [ 26 27 ] .
The first conclusion is related to the neurochemical properties of fluoxetine and clomipramine.
Although the effects of fluoxetine and clomipramine on flank marking were statistically significant in the drug comparison studies (Fig 1), the effects were limited to a 30-40% reduction.
As noted earlier, fluoxetine is a selective serotonin re-uptake inhibitor while clomipramine is a non-selective re-uptake inhibitor of serotonin, and to some extent norepinephrine.
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