Example sentences for: first-line

How can you use “first-line” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In the sixth report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC VI), peripheral alpha-1 antagonists are recommended not only as second-line anti-hypertensive therapy after low-dose diuretics and beta blockers, but also for specific indications such as therapy in men with hypertension and prostatism [ 2 ] . Alpha-1 antagonists represent effective therapy for prostatism, and fifty percent of men have histologic evidence of BPH by 60 years of age [ 3 4 ] . The National Ambulatory Medical Care Survey reported that the number of people on any type of peripheral alpha-1 antagonist in 1995 was approximately 6 to 7% of those with hypertension [ 5 ] . About 80% of surveyed physicians would choose these drugs as a first-line blood pressure agent for patients with hypertension and symptoms of BPH [ 6 ] .

  • Nevertheless, based on the results of this study and others, Uganda has chosen a combination of artemether and lumefantrine as its first-line therapy against malaria.

  • This study suggests that the first-line drug therapy for patients diagnosed with gastric ulcer should be a PPI, in preference to an H2 antagonist.

  • The Kenya National Malaria Guidelines state that SP is the first-line drug for uncomplicated malaria in all age groups and should be taken with an anti-pyretic.

  • On a more positive note, prescription of thiazides as a first-line therapy rose over the study period—from 25% to 42% in patients without comorbidities.


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