Words similar to filopodial
Example sentences for: filopodial
How can you use “filopodial” in a sentence? Here are some example sentences to help you improve your vocabulary:
The C3 induced extensions were rich in filamentous actin, and C3 treated HPB-ALL cell bodies apparently lacked filopodial actin microspikes, present in normal spreading cells.
have shown that, initially, many filopodial extensions arise from one cell and are directed toward a neighbour.
It is generally accepted that the driving force for cell movement is provided by the dynamic reorganization of the actin cytoskeleton, directing protrusion (lamellipodia and filopodia) at the front of the cell and retraction at the rear [ 30 31 ] . Although we have not examined the ultrastructure of the dermal fibroblasts at the edge of wound sites, we showed previously by electron microscopy that in the lens of SPARC-null mice numerous cellular processes extended into the ECM of the lens capsule [ 23 ] . We further showed that, in contrast to the abnormal filopodial projections at the lens cell-ECM interface, cell-cell contacts between the neighboring lens epithelial cells and between the lens epithelial and fiber cells were normal [ 23 ] . The results indicate that disassembly of cell-cell contacts between lens cells is not taking place, despite the forward movement of the lens cells into the ECM of the capsule.
Perhaps components required for nucleation are de-localized by BDM allowing new polymerization to be re-directed to filopodia, as filopodial extension is thought to be driven by elongation and not nucleation [ 27 ] . The extension of the growth cone itself could result from a similar diversion of actin monomer from nucleation of new filaments to extension of existing filaments.
Data from studies of in vivo and in vitro filopodia formation suggest that they develop as a reorganization of the dendritic network in which they exist [ 29 30 ] . In the presence of proteins that bundle and reorganize actin filaments into filopodial precursors, the de-localization of Arp2/3 and other leading edge components may lead to the formation of filopodia, which are then elongated as described above.
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