Example sentences for: filopodia

How can you use “filopodia” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A particularly clear example of this is the use of actin cytoskeleton as a “wool” for knitting multiple dynamic structures such as lamellae, filopodia, and stress fibres.

  • While the transiently occurring filopodia and retraction fibers can largely be distinguished only by time-lapse video microscopy [ 22], both, micropodia and lamellipodia, are functionally related to movement of cells.

  • Filopodia formation of short filamentous actin microspikes gives way to membrane ruffling and lamellipodia formation, culminating in the organized production of actin stress fibers.

  • In the Aplysia bag cell neuron, BDM application leads to extension of filopodia and the growth cone itself.

  • The involvement of Rho GTPases in regulating integrin dependent events such as leukocyte homotypic aggregation and in chemokine upregulation of integrin-mediated adhesion has recently been identified [ 18 19 ] . ADP-ribosylation of Rho in neutrophils by treatment with C3 not only inhibits cellular locomotion, but augments chemoattractant induced actin polymerization [ 20 21 ] . Moreover, inactivation of Rho in monocytic cells leads to accelerated formation of filopodia, and it has been proposed that Rho is a negative regulator of actin polymerization within this cell type [ 22 ] . Active Rho is also required for normal morphology, motility, and cytolytic activity of IL-2 activated NK cells [ 23 24 ] . We and others have demonstrated the importance of Rho in T lymphocyte activation [ 25 26 ] . Given the role played by Rho in the regulation of actin microfilaments in other cell types, and the indispensability of a functional actin cytoskeleton in lymphocyte motility and activation, it is of importance to study Rho's role in the regulation of T lymphocyte integrin function and maintenance of cytoskeletal organization.


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