Example sentences for: filopodia

How can you use “filopodia” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The filopodia of spreading 3T3 cells were extensively studied by Albrecht-Buehler et al [ 21, 27, 29], but ultramicroextensions were not described presumably because these studies were carried out during early spreading of 3T3 cells.

  • It is generally accepted that the driving force for cell movement is provided by the dynamic reorganization of the actin cytoskeleton, directing protrusion (lamellipodia and filopodia) at the front of the cell and retraction at the rear [ 30 31 ] . Although we have not examined the ultrastructure of the dermal fibroblasts at the edge of wound sites, we showed previously by electron microscopy that in the lens of SPARC-null mice numerous cellular processes extended into the ECM of the lens capsule [ 23 ] . We further showed that, in contrast to the abnormal filopodial projections at the lens cell-ECM interface, cell-cell contacts between the neighboring lens epithelial cells and between the lens epithelial and fiber cells were normal [ 23 ] . The results indicate that disassembly of cell-cell contacts between lens cells is not taking place, despite the forward movement of the lens cells into the ECM of the capsule.

  • Perhaps components required for nucleation are de-localized by BDM allowing new polymerization to be re-directed to filopodia, as filopodial extension is thought to be driven by elongation and not nucleation [ 27 ] . The extension of the growth cone itself could result from a similar diversion of actin monomer from nucleation of new filaments to extension of existing filaments.

  • While the transiently occurring filopodia and retraction fibers can largely be distinguished only by time-lapse video microscopy [ 22], both, micropodia and lamellipodia, are functionally related to movement of cells.

  • In the literature, terms such as slender filopodia [ 34, 35], or slender microvilli [ 36, 37] have been used.


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