Words similar to filopodia
Example sentences for: filopodia
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The thick actin rich stellate projections emanating from the cell body of C3 electroporated HPB-ALL may be the result of condensation of filopodia, where Cdc42 may be induced into a highly active state.
Control electroporated cells display rather diffuse filamentous actin staining in elongated pseudopodial processes that flatten and spread out on their termini, and there are multiple filopodia extending from these processes and from the cell body (figure 5A, arrows).
Data from studies of in vivo and in vitro filopodia formation suggest that they develop as a reorganization of the dendritic network in which they exist [ 29 30 ] . In the presence of proteins that bundle and reorganize actin filaments into filopodial precursors, the de-localization of Arp2/3 and other leading edge components may lead to the formation of filopodia, which are then elongated as described above.
We use the term "micropodia" here for morphologically describing filopodia, microspikes, and retraction fibers, and to differentiate these structures from lamellipodia.
It is generally accepted that the driving force for cell movement is provided by the dynamic reorganization of the actin cytoskeleton, directing protrusion (lamellipodia and filopodia) at the front of the cell and retraction at the rear [ 30 31 ] . Although we have not examined the ultrastructure of the dermal fibroblasts at the edge of wound sites, we showed previously by electron microscopy that in the lens of SPARC-null mice numerous cellular processes extended into the ECM of the lens capsule [ 23 ] . We further showed that, in contrast to the abnormal filopodial projections at the lens cell-ECM interface, cell-cell contacts between the neighboring lens epithelial cells and between the lens epithelial and fiber cells were normal [ 23 ] . The results indicate that disassembly of cell-cell contacts between lens cells is not taking place, despite the forward movement of the lens cells into the ECM of the capsule.
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