Words similar to fbn

Example sentences for: fbn

How can you use “fbn” in a sentence? Here are some example sentences to help you improve your vocabulary:

To determine whether the low value for synthesis was due to reduced mutant transcript levels, we made use of the Rsa I restriction site polymorphism in the FBN1 3'UTR for which the patient is heterozygous.
4%) exon skipping mutations, and 4 other mutations, as listed in the Human Gene Mutation Database (HGMD, http://archive.uwcm.ac.uk/uwcm/mg/search/127115.html) [ 4 ] and reported more recently [ 5 ] . Although the FBN1 gene, including three alternatively spliced 5' untranslated exons [ 6 ] extends over 235 kb of genomic DNA in chromosome band 15q21.
The blots were hybridized successively with the three overlapping long-range RT-PCR fragments covering the FBN1 coding region, that were generated from a normal cDNA template as described above.
Of those, 1166 (5%) are gross deletions http://archive.uwcm.ac.uk/uwcm/mg/hgmd0.html [ 27 ] suggesting that more FBN1 genomic deletions await recognition.
Genomic DNA and total RNA were extracted from fibroblast cultures established from skin biopsies as described [ 14 ] . Long-range RT-PCR amplification of FBN1 cDNA fragments and restriction enzyme digestions were performed as previously reported [ 8 ] . Fragments migrating abnormally in agarose gel electrophoresis were excised, purified with the QIAquick Gel Extraction Kit (QIAGEN) and directly sequenced with fluorescent terminators on an ABI Prism 377 DNA sequencer (Perkin-Elmer).