Words similar to fba
Example sentences for: fba
How can you use “fba” in a sentence? Here are some example sentences to help you improve your vocabulary:
Conditionally essential genes : During the growth simulations with external parameters defined by the LO, there were genes defined as critical for growth; however, many of these genes were essential for cellular growth upon oxygen limitations ( fba, pfkAB, tpiA, eno, gpmAB ). These genes were termed conditionally essential.
However, FBA does have predictive capabilities when a physiologically meaningful objective function can be defined, and the E. coli FBA results, with maximal growth rate as the objective function, have been shown to be consistent with experimental data under nutritionally rich conditions [ 40].
Therefore, herein we have utilized E. coli in silico to computationally examine the condition dependent optimal metabolic pathway utilization, and we will show that the FBA can be used to analyze and interpret the metabolic behavior of wildtype and mutant E. coli strains.
These case studies were chosen to further investigate the metabolic genotype-phenotype relation in silico and to demonstrate the use of FBA to interpret and analyze cellular metabolism.
The fba -, pfkAB -, and tpiA - in silico deletion strains had a limited capability to synthesize glyceraldehyde 3-phosphate, 3-phosphoglycerate, phosphoenolpyruvate, pyruvate, acetyl-CoA, α-ketoglutarate, succinyl-CoA, oxaloacetate, and high-energy phosphate bonds in all phases, and were completely unable to synthesize many of the biosynthetic precursors in phases 46 (Table 1) ( tpi - in silico strain discussed below).
Loading...