Words similar to fasl
Example sentences for: fasl
How can you use “fasl” in a sentence? Here are some example sentences to help you improve your vocabulary:
Expression of both Fas and FasL was observed in kidneys of both SD and S rats, but specifically increased over time in hypertensive S rats.
Augmented expression of both Fas and FasL by glomerular and tubular cells resulted in caspase-8 activation.
These data, along with the previous studies that confirmed morphological evidence of apoptosis and biochemical evidence of caspase-3 activation in these kidneys [ 7 ] , showed a role for the Fas/FasL pathway in promoting the loss of kidney function that develops in the setting of hypertensive nephrosclerosis in this model.
Indeed, tumor necrosis factor α (TNFα), interferon gamma (IFNγ) and/or interleukin-1 beta (IL-1β) have all been shown to reduce gonadotrophin-induced progesterone synthesis in a number of species [ 8 9 10 11 12 ] , and TNFα and IFNγ are known to increase PGF 2α production by steroidogenic cells [ 13 14 15 ] . Steroidogenic cell apoptotic paradigms are activated by cytokines generated by several cell types within the CL, including immune cells and endothelial cells [ 7 11 16 ] . The synergistic actions of IFNγ and TNFα, for example, induce steroidogenic cell apoptosis [ 13 17 ] , as does soluble Fas ligand (FasL) [ 18 19 20 21 22 23 24 25 26 ] . Furthermore, several acute intracellular signaling events either required for, or associated with, the functional and structural aspects of luteal regression have been mapped using in vitro steroidogenic cell cultures [ 8 27 28 ] .
Quantification of these observations showed an increase in expression of FasL in both glomerular and tubular compartments of kidneys of S rats on the 8.0% NaCl diet, compared with the other three groups (Fig.
Loading...