Example sentences for: fasl

How can you use “fasl” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Associated with the increased expression was cleavage of procaspase-8 to produce the active enzyme and cleavage of Bid, indicating activation of the Fas/FasL apoptotic pathway in the course of progressive renal failure.

  • After incubation for 10 min in the Doublestain Block (DAKO) at room temperature, the specimens were incubated for 30 min with the goat anti-FasL IgG (Santa Cruz Biotechnology, Inc.), 1:50 dilution in PBS containing 1% BSA.

  • The eyes of mice lacking functional FAS or FASL were similar in appearance to eyes from age-matched B6 mice (not shown).

  • These data, along with the previous studies that confirmed morphological evidence of apoptosis and biochemical evidence of caspase-3 activation in these kidneys [ 7 ] , showed a role for the Fas/FasL pathway in promoting the loss of kidney function that develops in the setting of hypertensive nephrosclerosis in this model.

  • To determine if absence of the cell death mediators FAS and FASL alter iridocorneal angle development and morphology, we assessed five mice (approximately P70) of each of the mutant strains B6.MRL- Fas lpr and B6Smn.C3H- Fasl gld , which respectively lack functional FAS and FASL [ 55, 56, 57, 58].


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