Words similar to fak

Example sentences for: fak

How can you use “fak” in a sentence? Here are some example sentences to help you improve your vocabulary:

One of the established in vivo substrates of PTEN, FAK, is known to play a major role in growth-regulatory signal transduction initiated by cell surface integrin receptors [ 48 49 ] . As we observe a correlation between increased PTEN activity and decreased levels of FAK phosphorylation (compare Figure 4Band Figure 5), it is likely that the dephosphorylation of FAK in response to the disruption of cell-matrix interactions is accomplished by increased PTEN activity.
Indeed, TGFβ 1 antibodies, cytochalasin D and BAPTA-AM [ 66 ] abolished the association on the cytoskeleton connected with integrin α V β 6 and activation of p125 FAK.
Activation of p125 FAK, a central step in integrin-associated signaling [ 72 73 ] , was determined to assess integrin-mediated signaling.
In parallel, phosphorylation of FAK, a known target of PTEN, is greatly reduced.
The overall amount of FAK protein in these cells did not change under these conditions, indicating that the loss of tyrosine phosphorylation was not caused by reduced amounts of protein.