Words similar to fak
Example sentences for: fak
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By contrast, tyrosine phosphorylation of endogenous Cas and FAK was unaffected by the Cas chimera, indicating that these processes lie upstream of the tyrosine phosphorylated Cas SD.
For a number of GPCRs, including the lysophosphatidic acid (LPAR) [ 7 ] , β-adrenergic 2 (β 2 -AR) [ 8 ] and μ- and δ-OR receptors [ 9 ] , the activation of a non-receptor tyrosine kinase of the Src or focal adhesion kinase (FAK) [ 10 ] families are involved.
In parallel, phosphorylation of FAK, a known target of PTEN, is greatly reduced.
Figure 7bdemonstrates that there was no difference in tyrosine phosphorylation or association with tyrosine phosphorylated proteins of either FAK or endogenous Cas upon stable expression of the tyrosine phosphorylated Cas SD chimera.
The following antibodies were used in a dilution of 1:1,000: TGFβ 1 (Santa Cruz [sc], sc-146), p-Tyr (sc-7020), β 6 -integrin (sc-6632), α V -integrin (sc-6617), p125 FAK(sc-557), TGFβ 1 -RI (sc-402), TGFβ 1 -RII (sc-400-G), ERK1/2-P (sc-7383), SMAD2/3 (sc-6033), SOS1/2 (sc-259), p130 cas(UBI-06-500), PCNA (sc-56), p21 WAF1(sc-6246), p27 KIP(sc-1641), c-fos (sc-7202), c-jun (sc-44), raf1 (sc-133), p21 Ras(sc-35) and phospho-threonine antibody (New England Biolabs, # 9381).