Words similar to factor-β
Example sentences for: factor-β
How can you use “factor-β” in a sentence? Here are some example sentences to help you improve your vocabulary:
The myeloblastin protein displays anti-proliferative properties and is also a key protease involved in factor-independent growth of hematopoietic cells [ 18 ] . Overexpression of myeloblastin has been linked to multifunctional cytokine transforming growth factor-β (TGF-β) a known regulator of angiogenesis.
For example, PPARγ agonists were shown to protect cytokine-induced PCD in cerebellar granule cells [ 59 ] . These agents could also block the neurotoxic effects caused by β-amyloid activated microglia, and thus might be beneficial in the treatment of Alzheimer's disease [ 60 ] . In non-neuronal tissues, PPARα activation was shown to suppress both spontaneous rat hepatocyte PCD and the PCD induced by transforming growth factor-β1 [ 61 ] .
In the absence of SPARC, expression of transforming growth factor-β1 and type I collagen is down-regulated in kidney mesangial cells [ 15 ] . The expression of cell surface receptor for insulin-like growth factor I in SPARC-null embryonic fibroblasts is also diminished [ 16 ] . Studies with SPARC-null cells have confirmed that SPARC functions in cell proliferation.
The bone morphogenetic protein (BMP) family including ligands, receptors, and binding proteins, has emerged as a central player in ovary physiology and female fertility [ 1 ] . The BMPs represent a large subclass of the transforming growth factor-β (TGF-β) surperfamily of ligands whose biological responses are mediated by Ser/Thr kinase receptors via the Smad-signaling molecules [ 2 ] . The mRNAs encoding several BMP family members have been identified in the murine ovary, including the ligands, BMP-2 [ 3 ] , BMP-3 [ 3 ] , BMP-3b [ 3 ] , BMP-4 [ 4 ] , BMP-6 [ 5 ] , BMP-7 [ 4 ] , BMP-15 [ 6 7 8 ] , the BMP receptors, BMPR-IA, BMPR-IB and BMPR-II [ 4 ] and the BMP binding protein, follistatin (FS) [ 9 ] . In the murine, BMP-4 and -7 mRNA have been identified in the theca interstitial cells [ 4 ] , BMP-6 and -15 in oocytes [ 5 6 7 8 ] , BMPR-IA, BMPR-IB and BMPR-II in oocytes and granulosa cells (GCs) [ 4 ] , and FS in granulosa and lutein cells [ 9 10 ] .
Various growth factors such as angiopoietin (ang)-1, platelet-derived growth factor, transforming growth factor-β as well as VEGF-A are also involved in arteriogenesis, and it may therefore be necessary to use combinations of these factors to obtain stable and mature vessels (Fig.
Loading...