Example sentences for: factor-

How can you use “factor-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Human activating transcription factor-2 (ATF-2): a predicted histone acetyltransferase

  • Insulin-like growth factor-1 may promote insulin secretion and prevent apoptosis of β-cells in vivo [36], and addition of this factor at stage 4 reduced apoptosis approximately 10-fold (see Figure 1A; data not shown).

  • Moreover, the Hypoxia Inducible Factor-1α (HIF-1α) has been identified as a master regulator for the expression of genes involved in essential hypoxic responses that maintain ATP levels in cells.

  • Delivery of intracellular modulators for therapeutic angiogenesis, including transcription factors that control angiogenesis such as hypoxia inducible factor-1 alpha (HIF-1α), is only possible through gene therapy.

  • An inhibitory effect of USF on Myc-mediated cellular proliferation has been demonstrated in HeLa cells [ 33 ] , and a non-canonical HLH element inhibits expression of the fibroblast growth factor binding protein (FGF-BP) in several carcinoma cells [ 34 ] . Furthermore, USF2 inhibits binding of hypoxia-inducible factor-1 (HIF-1) to the plasminogen activator inhibitor -1 (PAI-1) gene in hepatocytes in order to disturb transcriptional activation [ 35 ] . Our results add C/EBPβ-mediated activation of RIIβ to the mechanisms inhibited by USF.


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