Words similar to exocrine
Example sentences for: exocrine
How can you use “exocrine” in a sentence? Here are some example sentences to help you improve your vocabulary:
The disease is commonly but variably expressed in the lungs, the exocrine pancreas, and the gastrointestinal mucosa [ 5 6 ] .
Cystic fibrosis (CF) is a generalized exocrine disease resulting from the defective regulation of epithelial chloride ion transport within various organ systems, most importantly the lungs [ 1 2 3 4 ] . This dysfunction can arise from a variety of mutations within the cystic fibrosis transmembrane conductance regulator (CFTR) gene on chromosome 7, which encodes the transmembrane pump responsible for regulating transepithelial ion levels [ 1 2 4 ] . This defect is associated with an increased viscosity of the airway surface fluid, and according to some studies, an altered salt concentration [ 5 6 ] . These and other pleiotropic effects of the CF gene abnormality increase the susceptibility of CF patients to bronchopulmonary bacterial infection by opportunistic pathogens.
A specific combination of β and γ subtypes may play such a role; however, one thorough study showed a lack of βγ on Golgi membranes of exocrine pancreatic cells even though a variety of Gα were readily detected in the Golgi [ 33 ] . Other proteins that may specifically promote the intracellular targeting of Gα have not been identified.
Other authors had proposed that SS associated with PBC should be considered a form of secondary SS that resembles more the "sicca complex" with exocrine features seen in patients with rheumatoid arthritis [ 40 41 ] .
It is important to note that HCV appears to account for a subgroup of patients with exocrine complaints in which half the cases might meet the definition for SS according to European and Manthorpe criteria.
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