Example sentences for: exocrine

How can you use “exocrine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The disease is commonly but variably expressed in the lungs, the exocrine pancreas, and the gastrointestinal mucosa [ 5 6 ] .

  • A specific combination of β and γ subtypes may play such a role; however, one thorough study showed a lack of βγ on Golgi membranes of exocrine pancreatic cells even though a variety of Gα were readily detected in the Golgi [ 33 ] . Other proteins that may specifically promote the intracellular targeting of Gα have not been identified.

  • Cystic fibrosis (CF) is a generalized exocrine disease resulting from the defective regulation of epithelial chloride ion transport within various organ systems, most importantly the lungs [ 1 2 3 4 ] . This dysfunction can arise from a variety of mutations within the cystic fibrosis transmembrane conductance regulator (CFTR) gene on chromosome 7, which encodes the transmembrane pump responsible for regulating transepithelial ion levels [ 1 2 4 ] . This defect is associated with an increased viscosity of the airway surface fluid, and according to some studies, an altered salt concentration [ 5 6 ] . These and other pleiotropic effects of the CF gene abnormality increase the susceptibility of CF patients to bronchopulmonary bacterial infection by opportunistic pathogens.

  • Other authors had proposed that SS associated with PBC should be considered a form of secondary SS that resembles more the "sicca complex" with exocrine features seen in patients with rheumatoid arthritis [ 40 41 ] .

  • Calnexin, Calreticulin, GRP94 (glycoprotein 96) and GRP78 (BiP) have been identified on the cell surface of immature thymocytes [ 16 17 ] . Cell surface expression of GRP94 is found in lymphocytes and lymphoid-like cells from several vertebrate species and is phylogenetically conserved [ 18 ] . Calnexin has been found on the surface of pro-B cells [ 19 ] , as well as in a variety of mammalian culture cells [ 20 ] and a number of HSPs are found expressed on the cell surface in human and murine tumor cells [ 21 22 23 24 ] . Calreticulin, GRP78 and PDI were described on the plasma membrane of different cell types [ 25 26 27 28 ] ; GRP78, GRP94, and PDI, have been found on the surface of rat exocrine pancreatic cells [ 29 30 ] , and GRP78 cell surface expression was recently shown in human endothelial cells [ 31 ] .


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