Words similar to excitability
Example sentences for: excitability
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Fatigue is associated with a compression of the PSD of the SEMG toward lower frequencies, from the very beginning of the voluntary contraction [ 5 ] . This is due to the reduction in the conduction velocity in direct relation with the muscular fiber membrane excitability and with neural adaptations, resulting in an increase of the lower frequency content of the signal.
A better understanding of the underlying mechanisms of febrile seizures might lead to new strategies of prevention or treatment [ 4 ] . Recent work has identified several genes associated with familial febrile seizure tendencies [ 5 6 7 ] . Some of these genes code for ion channels that govern excitability of nerve tissue.
These results provide a novel insight of modulation mechanism of insulin secretion by PMA, increases insulin secretion by activation of PKC, and meanwhile decrease insulin secretion by impairing β-cell excitability in a PKC-independent manner in rat pancreatic β-cells.
Genes associated with the cell cytoskeleton, positive and negative regulators of apoptosis as well as immune markers tend to be up-regulated, whereas genes involved in membrane excitability (ion channels) or neurotransmission (neurotransmitters and vesicle trafficking genes) tend to be down-regulated.
Metabotropic glutamate receptors (mGluRs) are a family of class 3 G protein-coupled receptors with important functions in the regulation of synaptic transmission, plasticity, neuronal excitability, and the regulation sensory transduction [ 1 2 3 4 5 ] . The eight mGluRs (mGluR1-8) and their splice variants have been divided into three groups (I-III) based on sequence homology, pharmacology and G protein coupling profiles [ 3 6 7 ] . Group II (mGluR2 and 3) and III (mGluR4, and 6 through 8) couple negatively to adenylate cyclase through activation of the G i/o family of G proteins [ 8 ] . Group I mGluRs (mGluR1 and 5) couple to multiple G proteins in native and heterologous systems, and have been observed to couple to G q/11 , G i/o and/or G s [ 9 10 11 12 13 14 15 ] . mGluRs appear to be important mediators of synaptic transmission in the brain.
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