Example sentences for: exacerbated

How can you use “exacerbated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In CIA and some other organ-specific autoimmune diseases, IFN-γ functions in a protective role, so that in IFN-γ-deficient mice disease is exacerbated [ 29, 30].

  • There is noticeable scatter from the expected diagonal, and the scatter is greatly exacerbated at low signal levels.

  • The effects of mefloquine on ER calcium homeostasis have been examined previously [ 5 6 ] . In experiments with isolated rabbit skeletal muscle microsomes, mefloquine was found to inhibit the uptake of calcium, with an IC 50 of approximately 43 μM [ 6 ] . This effect was exacerbated by treatment with thapsigargin, a specific inhibitor of the ER calcium pump [ 6 ] . Further, the rate of ATP hydrolysis by the ER Ca 2+-ATPase was reduced in the presence of mefloquine (Ki of = 53 μM).

  • Arthritis severity in IL-10 -/-mice was significantly exacerbated in comparison with that of WT or IL-10 +/-mice (Fig.

  • These factors are exacerbated by limited timeframes that may constrain available compliance options and thwart long range planning.


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