Example sentences for: esx

How can you use “esx” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, TGFβ downregulated Ese-1/Esx mRNA levels faster than it upregulated Smad7 expression excluding the possibility that Smad7 mediates the TGFβ effect on Ese-1/Esx, at least at the initial phase.

  • Furthermore, we show for the first time that, in breast cancer cells, the Ese-1/Esx mRNA is downregulated by TGFβ.

  • Ese-1/Esx is a member of the Ets transcription factor family and is expressed mainly in epithelial tissue [ 30 ] . Its expression has been detected during mammary gland development and breast tumorigenesis [ 47 48 ] . It is noteworthy that Ese-1/Esx is a potential transcriptional regulator of the TGFβ type II receptor [ 31 ] and overexpression of Ese-1/Esx in non-invasive cells leads to a reduction in cell growth in the presence of TGFβ, presumably because of an increased TGFβ type II receptor level [ 49 ] . It is interesting that TGFβ-dependent downregulation of Ese-1/Esx is not affected by SB-203580.

  • We present data showing that TGFβ downregulated the Ese-1/Esx transcript, a novel and yet unpublished finding.

  • Ese-1/ Esx forward 5' CAGGGCAGCTTGGAAGAG 3'


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