Example sentences for: est

How can you use “est” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • While tissue expression patterns suggest five candidates that are highly expressed in brain - one with a known association with neurological disease - neither the RT-PCR data nor the EST information can absolutely rule out any of the 19 as culpable candidates.

  • Predicting the structure of genes for which no EST/cDNA data exists will require alternative approaches, such as comparative gene modeling among divergent species with conserved proteomes in the same group of organisms.

  • EST sequences are available from GenBank, EMBL and DDJB under the accession numbers AW440989-AW441125, AW570643-AW571393, AW588598-AW588988, AW589050-AW589115, AW735503-AW735730, AW782981-AW783662, AW827629-AW830045, AW870657-AW871697, and BI773381-Bl773521.

  • Custom scripts evaluated assemblies for: 5' and 3' EST reads in a single contig in the proper orientation; at least 10 bases of 3' poly(A) tail; phrap estimated error rate of less than one in 50,000 bases; and individual base quality of at least q25.

  • In a few cases we had enough cDNA and EST data to indicate that RNA editing is the most likely explanation for the observed variation.


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